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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
9.09
Human Site:
T749
Identified Species:
13.33
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T749
K
R
R
K
M
K
K
T
S
T
S
T
E
T
R
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T841
K
R
R
K
M
K
K
T
S
T
S
T
E
T
R
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T1001
K
R
R
K
M
K
K
T
S
T
S
T
E
T
R
Dog
Lupus familis
XP_547953
806
90703
K754
L
A
K
R
R
K
M
K
K
T
S
T
S
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
F717
N
R
G
K
R
E
G
F
F
L
K
S
V
E
N
Rat
Rattus norvegicus
Q63531
735
82865
Q683
T
Q
K
D
K
L
P
Q
S
Q
L
S
H
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
R661
K
A
P
L
A
K
R
R
K
M
K
K
T
S
T
Chicken
Gallus gallus
Q5F3L1
789
89022
K737
L
A
K
R
R
K
M
K
K
T
S
T
S
T
E
Frog
Xenopus laevis
P10665
733
82620
Q681
T
K
R
D
A
L
P
Q
S
Q
L
N
R
Q
D
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Q687
R
D
Q
N
P
H
F
Q
L
T
R
H
E
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Q1042
R
R
P
R
T
R
Q
Q
R
R
T
E
S
Q
L
Honey Bee
Apis mellifera
XP_395099
910
102507
E831
K
K
R
R
K
R
D
E
D
E
E
T
K
S
K
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Q711
K
R
R
G
I
K
R
Q
S
G
D
K
D
A
S
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
K707
A
K
R
R
K
K
K
K
D
S
S
T
E
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
R419
F
K
P
A
V
S
G
R
Q
C
I
A
N
F
D
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
D625
P
I
V
K
S
E
I
D
T
A
N
F
D
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
33.3
N.A.
13.3
6.6
N.A.
13.3
33.3
13.3
13.3
N.A.
6.6
20
33.3
53.3
P-Site Similarity:
100
100
100
46.6
N.A.
26.6
26.6
N.A.
26.6
46.6
20
26.6
N.A.
40
60
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
19
0
7
13
0
0
0
0
7
0
7
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
13
0
0
7
7
13
0
7
0
13
0
19
% D
% Glu:
0
0
0
0
0
13
0
7
0
7
7
7
32
7
19
% E
% Phe:
7
0
0
0
0
0
7
7
7
0
0
7
0
7
0
% F
% Gly:
0
0
7
7
0
0
13
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
7
7
0
0
% H
% Ile:
0
7
0
0
7
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
38
25
19
32
19
50
25
19
19
0
13
13
7
0
7
% K
% Leu:
13
0
0
7
0
13
0
0
7
7
13
0
0
0
7
% L
% Met:
0
0
0
0
19
0
13
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
0
0
7
7
7
0
7
% N
% Pro:
7
0
19
0
7
0
13
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
7
0
0
0
7
32
7
13
0
0
0
25
0
% Q
% Arg:
13
38
44
32
19
13
13
13
7
7
7
0
7
0
25
% R
% Ser:
0
0
0
0
7
7
0
0
38
7
38
13
19
13
7
% S
% Thr:
13
0
0
0
7
0
0
19
7
38
7
44
7
38
7
% T
% Val:
0
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _